Publications

Below are listed recent original publications. For older publications, or any further information please get in touch.

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Yan, J., Huang, B., Tonko, J., Toulemonde, M., Hansen-Shearer, J., Tan, Q., Riemer, K., Ntagiantas, K., Chowdhury, R.A., Lambiase, P. D., Senior, R. and Tang, M.

Transthoracic ultrasound localization microscopy of myocardial vasculature in patients. Nat. Biomed. Eng (2024). May.

 https://doi.org/10.1038/s41551-024-01206-6

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Sidik, N., McEntegart, M., Joshi, F., Owens, C., Shaukat, A., Gallagher, S., Strange, J., Tang, K., Elghamaz, A., Mozid, A., Ladwiniec, A., Oldroyd, K., Schuette, D., Copt, S., and Spratt, J.

Safety and Effectiveness of a Novel Microcatheter in Coronary Chronic Total Occlusions – The BIOMICS Study. JSCAI. 2024. May

https://doi.org/10.1016/j.jscai.2024.102017  

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Gvinianidze, G., Toulemonder, M., Hampson, R., Wakefield, L., Bioh, G., Tang, M. and Senior, R.

Feasibility of High Frame Rate Contrast-Enhanced Ultrasound for the Assessment of Ischaemic Heart Disease in Humans. J Am Coll Cardiol. 2024 Apr, 83 (13_Supplement) 1430. 

https://doi.org/10.1016/S0735-1097(24)03420-X

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Harmony Reynolds, Derek Cyr, C. Noel Bairey Merz, Leslee Shaw, Bernard Chaitman, William Boden, Karen Alexander, Yves Rosenberg, Sripal Bangalore, Gregg Stone, Claes Held, John Spertus, Kaatje Goetschalckx, Olga Bockeria, Jonathan Newman, Jeffrey Berger, Ahmed Elghamaz, Renato Lopes, James Min, Daniel Berman, Michael Picard, Raymond Kwong, Robert Harrington, Boban Thomas, Sean O’Brien, David Maron, and Judith Hochman. ISCHEMIA Research Group.

Sex Differences in Revascularization, Treatment Goals, and Outcomes of Patients with Chronic Coronary Disease: Insights from the ISCHEMIA Trial. J Am Heart Assoc. 2024;13:e029850. 

https://doi.org/10.1161/JAHA.122.029850

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Nobuhiro Ikemura, John Spertus, Dan Nguyen, Zhuxuan Fu, Philip Jones, Harmony Reynolds, Sripal Bangalore, Balram Bhargava, Roxy Senior, Ahmed Elghamaz, Shaun Goodman, Renato Lopes, Radoslaw Pracon, Jose Luis Lopez-Sendon, Aldo Pietro Maggioni, Shun Kohsaka, Gregory Roth, Harvey White, Kreton Mavromatis, William Boden, Fatima Rodriguez, Judith Hochman, and David Maron; ISCHEMIA Research Group.

International Variation in Health Status Benefits in Patients Undergoing Initial Invasive Versus Conservative Management for Chronic Coronary Disease: Insights from the ISCHEMIA trial. J Am Coll Cardiol. 2023 Mar, 81 (8_Supplement) 1111.

https://doi.org/10.1016/S0735-1097(23)01555-3

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Bioh, G., Botrous, C. & Senior, R.

Efficacy and safety of use of ultrasound enhancing agent in patients hospitalized with COVID-19. Int J Cardiovasc Imaging (2023). 

https://doi.org/10.1007/s10554-023-03032-4  

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Reinette Hampson, Roxy Senior , Liam Ring, Shaun Robinson, Daniel X Augustine, Harald Becher, Natasha Anderson, James Willis, Badrinathan Chandrasekaran, Attila Kardos, Anjana Siva, Paul Leeson, Bushra Rana, Navtej Chahal, David Oxborough.

Contrast echocardiography: a practical guideline from the British Society of Echocardiography. Echo Res Pract10, 23 (2023) 

https://doi.org/10.1186/s44156-023-00034-9 

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Johnson CL, Woodward W, McCourt A, Dockerill C, Krasner S, Monaghan M, Senior R, Augustine DX, Paton M, O’Driscoll J, Oxborough D, Pearce K, Robinson S, Willis J, Sharma R, Tsiachristas A, Leeson P; EVAREST/BSE-NSTEP Investigators

Real world hospital costs following stress echocardiography in the UK: a costing study from the EVAREST/BSE-NSTEP multi-centre study. Echo Res Pract. 2023 May 31;10(1):8.

https://doi.org/10.1186/s44156-023-00020-1

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Perera D, Ryan M, Morgan HP, Greenwood JP, Petrie MC, Dodd M, Weerackody R, O’Kane PD, Masci PG, Nazir MS, Papachristidis A, Chahal N, Khattar R, Ezad SM, Kapetanakis S, Dixon LJ, De Silva K, McDiarmid AK, Marber MS, McDonagh T, McCann GP, Clayton TC, Senior R, Chiribiri A; REVIVED-BCIS2 Investigators.

Viability and Outcomes With Revascularization or Medical Therapy in Ischemic Ventricular Dysfunction: A Prespecified Secondary Analysis of the REVIVED-BCIS2 Trial. JAMA Cardiol. 2023 Oct 25

doi:10.1001/jamacardio.2023.3803 

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Davis EF, Crousillat DR, Peteiro J, Lopez-Sendon J, Senior R, et al CIAO-ISCHEMIA Research Group.

Global Longitudinal Strain as Predictor of Inducible Ischaemia in No Obstructive Coronary Artery Disease in the CIAO-ISCHEMIA Study. J AM Soc Echocardiography (2023) 37(1) 89-99

 https://doi.org/10.1016/j.echo.2023.09.006

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Gurunathan S, Shanmuganathan S, Chopra A, Pradhan J, Aboud  L,Hampson R, Yakupoglu Y, Bioh G, Banfield A, Gage H,Khattar, Senior R

Comparative Effectiveness of Exercise Electrocardiography Versus Exercise Echocardiography in Women Presenting with Suspected Coronary Artery Disease: A Randomised Study. Eur Heart J Open. 2023 May 22;3(3). 

 

 https://doi.org/10.1093/ehjopen/oead053

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Maron DJ, Hochman JS, Reynolds HR, Bangalore S, O’Brien SM, Boden WE, Chaitman BR, Senior R, López-Sendón J, Alexander KP, Lopes RD, Shaw LJ, Berger JS, Newman JD, Sidhu MS, Goodman SG, Ruzyllo W, Gosselin G, Maggioni AP, White HD, Bhargava B, Min JK, Mancini GBJ, Berman DS, Picard MH, Kwong RY, Ali ZA, Mark DB, Spertus JA, Krishnan MN, Elghamaz A, Moorthy N, Hueb WA, Demkow M, Mavromatis K, Bockeria O, Peteiro J, Miller TD, Szwed H, Doerr R, Keltai M, Selvanayagam JB, Steg PG, Held C, Kohsaka S, Mavromichalis S, Kirby R, Jeffries NO, Harrell FE Jr, Rockhold FW, Broderick S, Ferguson TB Jr, Williams DO, Harrington RA, Stone GW, Rosenberg Y; ISCHEMIA Research Group.

Initiall Invasive or Conservative Strategy for Stable Coronary Disease. N Engl J Med. 2020 Apr 9;382(15):1395-1407.

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Fusco F, Shimada E, Scognamiglio G, Senior R, Gatzoulis MA, Babu-Narayan S, Li W.  Restrictive ventricular septal defect resulting in systemic outflow obstruction in adults with Fontan circulation.  Challenging diagnosis of a serious and potentially fatal complication. 

J Cardiovasc Med 2020; 21(3): 276-279

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Mushemi-Blake S, Surkova E, Hatipoqlu S, Senior R, Li W.  Severe regurgitation of a double-orifice left atrioventricular valve in a patient with repaired atrioventricular septal defect: Added value of 3D echocardiography.  Eur Heart J Cardiovasc Imaging 2020; 21(7): 814     

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Ahmadvazir S, Pradhan J, Khattar RS, Senior R. Long-Term Prognostic Value of Simultaneous Assessment of Atherosclerosis and Ischemia in Patients with Suspected Angina: Implications for Routine Use of Carotid Ultrasound During Stress Echocardiography

J Am Soc Echocardiogr 2020;33(5):559-569

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Halliday B, Senior R, Pennell D

Assessing left ventricular systolic function – from ejection fraction to strain analysis

            Eur Heart J 2020

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Chahal N, Senior

  Assessing Systolic Function In Aortic Stenosis: The Earlier The Better?

Heart 2020;106(16):1200-1201

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Ahmadvazir S, Pradhan J, Khattar RS, Senior R

Sex-based impact of carotid plaque in patients with chest pain undergoing stress echocardiography. Heart 2020 

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Nam MCY, Meneses ML, Byrne CD, Richman T, Quah JX, Bailey TG, Hickman I, Anstey C, Askew CD, Senior R, Stanton T, Russell AW, Greave K.  An experimental series investigating the effects of hyperinsulinemic euglycemia on myocardial blood flow reserve in healthy individuals and on myocardial perfusion defect size following st-segment elevation myocardial infarction. J Am Soc Echocardiogr 2020; ; 33:868

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Reynold HR, Shaw LJ, Min JK, Spertus JA, Chaitman BR, Berman DS, Picard MH, Kwong RY, Bairey-Nerz CN, Cyr DD, Lopes DD, Lopez- Sendon JL, Held C, Szwed H, Senior R, Gosselin G, Nair R, Elghamaz A, Bockeria O, Chen J, Chemyavskiy AM, Bhargava B, Newman JD, Hinic SB, Jaroch J, Hoye A, Berger J, Boden WE, O’Brien SM, Maron DJ, Ischemia Research Group.  

             Association of sex with severity of coronary artery disease, ischemia, and symptom burden in              patients with moderate or severe ischemia: secondary analysis of the ischemia randomized                 clinical trial.  JAMA Cardiol. 2020 Jul 1;5(7):773-786

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Dewey M, Siebes M, Kachelrieß M, Kofoed KF, Maurovich-Horvat P, Nikolaou K, Bai W, Kofler A, Manka R, Kozerke S, Chiribiri A, Schaeffter T, Michallek F, Bengel F, Nekolla S, Knaapen P, Lubberink M, Senior R, Tang MX, Piek JJ, van de Hoef T, Martens J, Schreiber L; Quantitative Cardiac Imaging Study Group.

Clinical quantitative cardiac imaging for the assessment of myocardial ischaemia.

Nat Rev Cardiol 2020;17(7):427-450

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Bioh G, Senior R. 

Stress echocardiography in the era of fractional flow reserve

Current Cardiovascular Imaging Reports 2020; 13(6)

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Danylenko O, Surkova E, Senior R, Li W

Unexpected mechanism of mitral regurgitation in a patient post ALCAPA repair:  Added value of three-dimensional echocardiography

Echocardiography 2020; 37: 1315-1317

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Senior R, Khattar RS

            Assessment of aortic stenosis: Time to go with the flow

Editorial Coment:  J Am Coll Cardiol 2020; 75 (15): 1770-1771

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Radhakrishnan A, Price AM, Pickup LC, Law JP, McGee KC, Fabritz L, Senior R, Steeds RP, Ferro CJ, Townend JN

Coronary flow velocity reserve and inflammatory markers in living kidney donors

 Int J Cardiol 2020 (in press)

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Yakupoglu HY, Saeed S, Senior R, Baksi AJ, Lyon AR, Khattar RS. Reversible exercise induced left ventricular dysfunction in symptomatic patients with previous Takotsubosyndrome: insights from stress echocardiography. 

Eur Heart J Cardiovasc Imaging. 2020 Sep 18: jeaa237. doi: 10.1093/ehjci/jeaa237. Online ahead of print

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Gurunathan S, Shanmuganathan M, Hampson R, Khattar R, Senior R.

Role of adjuvant carotid ultrasound in women undergoing stress echocardiography for the assessment of suspected coronary artery disease.

Open Heart 2020 (in press)

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Hochman JS, Reynolds HR, Bangalore S, O’Brien SM, Alexander KP, Senior R, Boden WE, Stone GW, Goodman SG, Lopes RD, Lopez-Sendon J, White HD, Maggioni AP, Shaw LJ, Min JK, Picard MH, Berman DS, Chaitman BR, Mark DB, Spertus JA, Cyr DD, Bhargava B, Ruzyllo W, Wander GS, Chernyavskiy AM, Rosenberg YD, Maron DJ; ISCHEMIA Research Group

Baseline Characterstics and Risk Profiles of Participants in the ISCHEMIA Randomized Clinical Trial

 JAMA Cardiol 2019; 4(3): 273-286

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Chong A, Senior R, Wahi S.

Contemporary Imaging of Aortic Stenosis                      

Heart Lung Circ 2019; 28(9): 1310-1319

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Newman JD, Alexander KP,Gu X, O’Brien SM, Boden WE, Govindan SC, Senior R, Moorthy N, Rezende PC, Demkow M, Lopez-Sendon JL, Bockeria O, Pandit N, Gosselin G, Stone PH, Spertus JA, Stone GW, Fleg JL, Hochman JS, Maron DJ. Baseline preictors of low-density lipoprotein cholesterol and systolic blood pressure goal attainment after 1 year in the ISCHEMIA trial.  Circ Cardiovasc Qual Outcomes 2019; 12(11):

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Vamvakidou An, Jin W, Danylenko O, Chahal N, Senior R.  Low transvalvular flow rate predicts mortality in patients with low-gradient aortic stenosis following aortic valve intervention. 

JACC Cardiovasc Imaging 2019; 12(9): 1715-1724

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Saeed S, Vamvakidou A, Seifert R, Khattar R, Li W, Senior R

The impact of aortic valve replacement on survival in patients with normal flow low gradient severe aortic stenosis:  A Propensity-Matched Comparison.  Eur Heart J – Cardiovasc Imaging 2019; 20(10):1094-1101

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Surkova E, West C, Liberty I, Flick C, Gatzoulis M, Senior R, Li, W

Added value of three-dimensional transthoracic echocardiography in assessment of an adult patient with atrioventricular septal defect.  Echocardiography 2019; 36(4):809-812

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Hochman J, Reynolds H,  Bangalore S, O’Brien S, Alexander K, Senior R, Boden W, Stone G, Goodman S, Lopes R, Lopez-Sendon J, White W, Maggioni A, Shaw L,  Min J , Picard M , Berman D ,Chaitman B , Mark D ,Spertus J , Cyr D , Bhargava B , Ruzyllo W , Wander G , Chernyavskiy A ,Rosenberg Y,Maron D.

Baseline Characteristics of Participants in the International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA). JAMA Cardiol 2019;4(3):273-286

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Hampson R, Vamvakidou A, Kinsey C, Singh B, Senior R.

Clinical effectiveness of a sonographer-led, cardiologist-interpreted stress echocardiography service in the rapid access stable chest pain clinic. Int J Cardiol. 2019; (281):107-112

 

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Senior R.  Paving the way for improving no-reflow phenomenon.  Int J Cardiol 2019; 15: 20-20

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Krupickova S, Li W, Cheang MH, Rigby ML, Uebing A, Daviouros P, Dimopoulos K, Di Salvo G, Fraisse A, Swan L, Alonso-Gonzalex R, Kempny A, Pennell DJ, Senior R Gatzoulis MA, Babu-Narayan SV. 

Ramipril and left ventricular diastolic function in stable patients with pulmonary regurgitation after repair of tetralogy of Fallot.  Int J Cardiol 2018;​

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Vamvakidou A, Jin W, Danylenko O, Pradhan J, Li Li W, West C, Khattar R,

Senior R 

Impact of pre-intervention transaortic flow rate versus stroke volume index on mortality across the hemodynmic spectrum of severe aortic stenosis

JACC Cardiovasc Imaging 2019; 12(1): 205-206

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Toulemonde MEG, Corbett R, Papadopoulou V, Chahal N, Li Y, Leow CH, Cosgrove DO, Eckersley RJ, Dunan N, Senior R. Tang MX. 

High frame-rate contrast echocardiography:  In-human demonstration.  JACC Cardovasc Imaging 2018; 11:  923-924.

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Shah BN, MacNab A, Lynch J, Hampson R, Senior R, Steed RP; BSE Stress Accreditatopm Committee. 

Stress echocardiography in contemporary clinical cardiology: practical considerations and accreditation.  Echo Res Pract.  2018; 5: E1-E6

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Porter TR, Mulvagh SL, Abdelmoneim SS, Becher H, Belcik JT, Bierig M, Choy J, Gaibazzi N, Gillam LD, Janardhanan R, Kutty S, Leong-Poi H, Lindner JR, Main ML, Mathias W Jr, Park MM, Senior R, Villanueva F. 

Clinical applications of ultransonic enancing agents in echocardiography:  2018.  ASE Guidelines update.  J Am Soc Echocardiogr 2018 31: 24-274